Bravecto Topical Solution for Cats defends against fleas and black-legged ticks for 12 weeks, and against American dog ticks for eight weeks. Bravecto Plus for Cats protects against fleas, black-legged ticks, heartworms, roundworms, and hookworms for eight weeks.

Active ingredients: fluralaner Bravecto Chew and Bravecto Topical Solution ; fluralaner and moxidectin Bravecto Plus. Known side effects: neurologic adverse reactions, including ataxia lack of coordination , seizures, and tremors; other known side effects—vomiting, hair loss, rash, lethargy, diarrhea, decreased appetite, dry skin, and itching.

Variants: Bravecto Chew for Dogs 4. Revolution Plus for Cats combats more pests—fleas, ear mites, roundworms, hookworms, and several species of ticks—than any other treatment we recommend. For versions suited to lighter or heavier cats, see below.

Unlike most other treatments, this formula kills fleas, and it also tackles ear mites, sarcoptic mange, and heartworms in dogs. But it treats only American dog ticks. For versions suited to lighter or heavier dogs, see below.

What it treats: Revolution Plus protects cats from more pests than our other picks. Like Bravecto , Revolution Plus also protects against common parasites in kittens, including roundworms and hookworms. It also works against fleas, black-legged ticks, American dog ticks, Gulf Coast ticks, ear mites, roundworms, hookworms, and heartworms.

Bravecto , Frontline , and Seresto do fight these. Revolution kills fleas, ear mites, sarcoptic mange, American dog ticks, and heartworms. Active ingredients: selamectin Revolution ; selamectin and sarolaner Revolution Plus. Known side effects: neurologic adverse reactions, including ataxia lack of coordination , seizures, and tremors.

Variants: Revolution for Dogs 5. Frontline Plus is our favorite non-prescription topical treatment, and it protects against fleas and a range of tick species. For dosing that is suitable for dogs of other weights, see below. This monthly non-prescription topical treatment for cats protects against the same pests as its counterpart for dogs and requires the same monthly schedule.

Consider this treatment if you have both dogs and cats, and you want to protect them from the same set of pests, on the same schedule. What it treats: Frontline Plus is the only flea and tick treatment we recommend that treats the same pests for cats or dogs, on the same timetable, without a prescription.

Both treatments fight fleas, lice, lone star ticks, American dog ticks, deer ticks, and brown dog ticks. Comparatively, Bravecto offers four formulas that protect against different combinations of pests, with less coverage in its cat products; this can get confusing for pet owners of both cats and dogs that want to protect their pets from several parasites with a single dose.

Frontline Plus takes out the guesswork so pet owners can focus on playtime rather than on flea-bath time. So you can quickly pick up a new box while running errands without worrying if your vet filled the prescription. Variants: Frontline Plus for Dogs 5 to 22 pounds , 23 to 44 pounds , 45 to 88 pounds , 89 to pounds ; Frontline Plus for Cats over 1.

This flea collar lasts up to eight months, and it protects against the same fleas and ticks as the dog version—but not lice and mange. The Seresto Collar for Dogs and Seresto Collar for Cats both provide protection that lasts as long as possible between reapplications eight months per collar, compared with one month for most topicals.

Half of our picks, including Frontline and Revolution, require monthly topical treatments. Also, some pets may not appreciate having the extra bulk of a collar around their neck.

And pets with especially sensitive skin may experience side effects of redness or inflammation near the collar; if this sounds like your pet, try an oral or topical treatment instead. Seresto Collar for Cats protects against fleas, American dog ticks, deer ticks, brown dog ticks, and lone star ticks.

Seresto Collar for Dogs protects against fleas, American dog ticks, deer ticks, brown dog ticks, lone star ticks, lice, and sarcoptic mange. Variants: Seresto Collar for Cats all pet weights ; Seresto Collar for Dogs up to 18 pounds , over 18 pounds. For this guide, I spoke with six professionals, from veterinarians to pesticide experts, about how to select the best flea and tick treatment for your pet.

I spoke with Jennifer Gervais, a pesticide specialist at the National Pesticide Information Center , and Ken Labbe, a spokesperson for the U.

Environmental Protection Agency about pesticide regulation. I consulted Dr. Douglas Kratt, president of the American Veterinary Medical Association , about how to select the appropriate medication for your pet.

I asked Dr. Tierra Price, a spay-neuter surgeon and founder of the BlackDVM Network , and Dr. Jennifer Welser, chief medical officer at Mars Veterinary Health , about their favorite flea and tick medications. And I discussed product safety with Dr. Tina Wismer, senior director of the ASPCA Animal Poison Control Center.

To find the best flea and tick treatments, we spoke with six pet and pesticide experts about medications, side effects, active ingredients, and regulatory concerns.

Our two veterinarians shared their personal product recommendations and shopping advice, which guided us in this review. They also shared the favorite treatments they recommend to their own clients. We cross-referenced their advice with dozens of treatments sold across retailers like PetMeds, Amazon, Chewy, Petco, and PetSmart, among others.

We dismissed sprays and shampoos because they offer protection for only days or a week at a time, and pet owners are more likely to misuse them compared with other products.

That left us with eight brands of chews, topicals, and collars for cats or dogs. We selected the four brands that were highly recommended by our experts, that kill and protect against a wide range of pests, and that are sold across retailers at a variety of budgets.

Pet owners who hike with their dogs have different needs than those who have house cats. All pesticides have risks, from skin irritation to seizures. We recommend only FDA-approved for ingested medications or EPA-registered for topicals treatments that both kill and protect against pests.

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Flea & Tick Control (40 Products Found) · Bravecto · Nexgard · Simparica Chewables · Revolution · Seresto Dog Collar · Simparica TRIO · Advantage Multi Flea and Tick Control for Dogs ; Nexgard. $ ; Bravecto. $ ; Frontline Plus. $ ; Simparica Chewables. $ ; Nexgard Spectra. $ Preventer Plus (Milbemycin oxime & Lufenuron) · Generic Advantage Multi (Imidacloprid & Moxidectin) · Revolution for Cats & Dogs · Generic Revolution for Cats

Reduced pet flea and tick treatments - A few of the best-loved flea medications are Credelio, Sentinel, Advantus, Capstar, Trifexis, Comfortis, Simparica, Nexgard, and Bravecto. Tractor Supply Flea & Tick Control (40 Products Found) · Bravecto · Nexgard · Simparica Chewables · Revolution · Seresto Dog Collar · Simparica TRIO · Advantage Multi Flea and Tick Control for Dogs ; Nexgard. $ ; Bravecto. $ ; Frontline Plus. $ ; Simparica Chewables. $ ; Nexgard Spectra. $ Preventer Plus (Milbemycin oxime & Lufenuron) · Generic Advantage Multi (Imidacloprid & Moxidectin) · Revolution for Cats & Dogs · Generic Revolution for Cats

Tick-prevention medications come in three main categories: oral chews, topical treatments you apply to the skin, and collars embedded with medication to repel ticks. Whichever method of prevention you prefer, all our experts agree that you should stick to newer classes of repellents and medications, since ticks have become resistant to certain chemicals over time.

For example, according to Dr. It definitely works for some, but not for all. Tick-prevention medications are designed to be poisonous to insects but not harmful to mammals like you, me, and our dogs. But because oral treatments are prescription medications and all tick treatments have potential side effects, even the ones sold over the counter, finding the best one for your dog should always start with a conversation with your vet, especially if you have a puppy, a toy breed dog, or a dog with preexisting health conditions.

For instance, some oral tick preventatives, including the ones mentioned below, are not recommended for dogs with a history of uncontrolled seizures. But Richardson, whose own dog takes one of the treatments on our list Nexgard , told us that the risk of seizures from taking tick prevention medication is rare and that the benefits far outweigh this risk.

That said, Richardson does recommend topical treatments for dogs with gastrointestinal issues. There are dozens of topical tick repellents on the market, many of which are sold over the counter.

Still, while you may find some for less money or see an all-natural spray that sounds safe to use at the pet store, you should always discuss the ingredients with your vet.

Since dogs come in a wide variety of sizes from teacup to giant breed, dog medications come in a variety of weight-based dosages. In general, this makes buying the safest and most effective medication possible for all dog owners. And since my own dog, Uli, weighs just five pounds — a size that is vulnerable to potential overdose — I put more trust in brands that offer clearly labeled options for many different sizes of dogs.

Depending on where you live the Northeast versus Alaska, for instance and how active your dog is, it might make more sense to give them one dose of medication that lasts several months instead of having to remember to give them their medication every month.

But for dogs who spend limited time in tick-infested areas, individual monthly doses could be convenient. The cost of each tick treatment varies depending on the brand and the length of protection provided. Bravecto was mentioned by all of the vets we talked to, with Waxman telling us her own dog takes the chewable oral treatment.

It is also what I give my five-pound dog Uli, whose gray fur makes finding ticks very difficult. According to the vets, its main appeal over other oral treatments is that it protects dogs from ticks and fleas for three months at a time, as opposed to one month at a time. To say Uli is a fan of Bravecto would be a lie, but she does happily eat the chew and it has kept her safe from fleas and ticks for many years.

He also says his dog never experiences any adverse side effects, like diarrhea or vomiting. Like Caos, Fable Pets co-founder Jeremy Canade gives Bravecto to his border collie Ranger and says he appreciates that the pup is always prepared for an impromptu hike or a trip to the park.

Most clinics will carry Bravecto, but you can order it online with a prescription from a veterinarian. It uses the same active ingredient that is found in chewable tablets, which means the topical will also protect your dog for three months at a time.

After trying a tick collar on her rescue Harmony, Strategist editor Maxine Builder switched to this oral option — which she calls a mess- and hassle-less treatment — and says it keeps her dog tick-free on summer trips to Maine a state where the tick-borne illness called babesiosis is considered an endemic in , according to the CDC.

Strategist writer Arielle Avila, who gets prescriptions delivered through Chewy, says her hound mix has been taking it for at least five years with no side effects; meanwhile, Strategist writer Latifah Miles says a veterinarian exclusively recommended Nexgard for her underyear-old Lab.

Strategist junior writer Brenley Goertzen also gives Nexgard to both her Great Dane and Aussie mix and likes that the medication is straightforward to administer because it can be given with food or on its own. Nexgard claims to kill or control black-legged ticks, American dog ticks, lone-star ticks, and brown dog ticks, which together account for the majority of ticks that dogs in the U.

will encounter. Avila says the monthly method is easy to remember, but both she and Miles set reminders on their phones to ensure their pets never miss a dose. Simparica Trio works against the same ticks and fleas as Nexgard and also protects your dog from heartworms, hookworms, and roundworms.

Three experts recommend it: Waxman, Brooks, and Dr. Like Nexgard, Simparica needs to be given to your dog every month, which Fadl says can be easier for some dog owners to remember.

She also says she prefers monthly prescriptions to those with a quarterly dose duration because, in her experience, the efficacy of the latter can diminish before the day mark.

Unlike other topical treatments, K9 Advantix can actually kill insects on contact. Waxman recommends it because it repels ticks and fleas, along with mosquitos, biting flies, and lice.

It is available for dogs who weigh as little as four pounds, and each application is effective for one month. Richardson and Caos also say non-ingested treatments like this are an excellent option for dogs with food allergies, but Caos warns that the active ingredients can be harmful to cats.

For example, in multi-pet households, a cat may rub against a treated dog, which can cause severe reactions and is sometimes fatal, Caos says.

Paola Cuevas, a veterinary consultant at Hepper and Pet Keen. PetArmor works to kill ticks, fleas, and lice within 48 hours of application, reducing the likelihood of blood-borne disease transmission.

For this reason, Cuevas recommends using it in conjunction with a repellent spray before going outdoors or bathing your pup in a flea-and-tick shampoo afterward. Cuevas says the active ingredients are also considered safe for dogs with the MDR1 genetic mutation, a condition that can cause serious reactions to some common drugs and affects approximately three of every four border collies.

Other herding breeds, including Australian shepherds, German shepherds, old English sheepdogs, long-haired whippets, and some mixed breeds, may also carry the genetic variant.

PetArmor is available for dogs who weigh five pounds up to pounds. Over time, as the chemicals wear off, the Seresto collar will release more for continued protection.

Stephanie Liff of Pure Paws Veterinary Care , who recommends the Seresto collar. Goertzen purchased this ultrasonic device after noticing it in several pet stores.

Although she already gives monthly doses of Nexgard to her Aussie mix, Goertzen says she wanted an added layer of chemical-free protection rather than using a tick collar.

Goertzen says the nontoxic repeller has provided extra peace of mind when taking her dog to highly wooded areas like northern Minnesota and Manitoba. If you still find a tick latched onto your dog after taking all the recommended precautions above, our experts say you should not try to pry it off with your fingers.

Veterinarian Dr. Thomas N. Pointed tweezers will get you as close as possible to the head of the tick, right next to the skin, without accidentally squeezing the bug. In general, topical spot-on and oral preventatives are the most effective flea control for dogs, but the Seresto collar might be a good option in certain situations.

Kelley Lay , a relief veterinarian in Nashville, Tennessee, says that traditional flea and tick collars are generally not very effective. She has even seen allergic reactions and other issues with some of them. However, she has found the Seresto collar safe and effective and recommends it to clients with pets who don't tolerate topical or oral flea and tick preventives.

The collar is nongreasy, odor-free, lightweight, and adjustable for dogs of all sizes. It can be worn alongside your dog's regular collar and has a two-step safety system to keep your dog safe if the collar gets caught on something.

The collar's active ingredients, imidacloprid and flumethrin , are released in low concentrations over your dog's skin and coat to kill fleas and ticks on contact — parasites do not need to bite your dog for the collar to work. You don't need to remove this water-resistant collar during swimming or bathing with one of the best dog shampoos.

Adams Plus kills fleas, flea eggs and larvae, ticks, and lice for up to 28 days while soothing dry, irritated skin. Our top pick for the best flea and tick shampoos for dogs is Adams Plus Flea and Tick Shampoo. In addition to killing fleas, flea eggs and larvae, ticks, and lice for up to 28 days, this shampoo soothes skin that has become dry and irritated from flea bites and constant scratching.

The shampoo contains pyrethrins and S-methoprene Precor synthetic pesticides commonly included in flea and tick shampoos. It also contains piperonyl butoxide to enhance the pesticides' effectiveness.

Oatmeal helps heal irritated and itchy skin, and the shampoo has a pleasant coconut scent. Lay says that flea shampoos are fine to use alongside prescription flea control medications but shouldn't be considered the first or best line of defense against fleas.

Veterinarian-prescribed, year-round flea prevention remains the gold standard. Despite marketing claims, these shampoos do not provide substantial flea protection after the bath and may leave dogs susceptible to repeated infestations. Some ingredients in shampoos can also irritate the skin. Safety and efficacy: FDA - or EPA-approved products have undergone rigorous safety and efficacy testing before going to market.

Number of parasites treated: Using a product that protects against more than just fleas is convenient. While your veterinarian can advise you on which product is best for your dog, we generally favor products that cover more parasites.

There are some exceptions. For instance, Capstar treats only fleas, but it is the only medicine available for puppies younger than 6 weeks.

OTC products, like Frontline Plus, protect against additional parasites such as ticks and lice but not heartworms. Products that treat heartworm always require a veterinary prescription. Ease of use: The easier it is to use a product, the better.

For example, chewable tablets are quick and easy to give your dog, provided they like the flavor. Products that require a person to wear gloves when they apply it or require the treated animal to stay away from children or other pets for a while may be a hassle.

Minimum age and weight: Flea treatments are intended for dogs above a minimum age and weight. Your options for a very young puppy will be more limited until they are older and weigh more.

Prescription vs. over-the-counter: Some flea control products are available over the counter. Others require a prescription from your veterinarian. You can buy prescription medicines from your veterinarian or online pet pharmacies and stores like Chewy, Petco, and PetSmart.

Prescription flea control products typically cost more than OTC options because they protect against more parasites, most importantly, deadly heartworms.

Dogs must test negative for heartworms before starting a heartworm preventive. Types of flea and tick medications: There are several types of treatments, including topical, oral, collars, shampoos, and sprays.

Cost, convenience, ease of use, and effectiveness vary among these products. Your vet can help you determine the best type for your dog. We advise against flea sprays because topical spot-ons and oral products are more effective.

Remember that some dogs with sensitive skin may not tolerate topical products. Crumley says that frequent bathing or swimming may also reduce the effectiveness of a topical product that remains on the skin's surface.

Natural vs. synthetic : Our experts do not recommend using natural products instead of veterinarian-recommended topical and oral flea control. While natural treatments can deter fleas and ticks, they won't eliminate an infestation.

If you also have kitties at home, avoid natural flea control products containing essential oils because some can be toxic to cats. Other pets in your home: Any product labeled for use in only dogs should never be given to a cat. Some ingredients can be toxic to cats.

While any dog-only flea product can harm felines, cats are especially sensitive to pyrethrins. If you're looking for a safe product for your cat, check out our guide to the best flea treatments for cats.

We consulted two veterinarians for advice regarding the treatment and prevention of fleas and other parasites in dogs. This information guided our selection of the best flea and tick treatments for dogs, but our experts did not endorse any of the products included in this guide unless explicitly quoted.

We also conducted research using the quick product reference guide published by the independent, nonprofit Companion Animal Parasite Council. This helpful reference includes all FDA- and EPA-approved parasite control products for small animals along with each product's active ingredients, directions for how to use it, and which parasites it controls.

Not only are fleas and ticks a big nuisance, they also carry diseases that can make dogs extremely ill. Although you may be tempted to use parasite preventives only in spring and summer, fleas, ticks, mosquitoes, and intestinal parasites are resilient.

Veterinarians recommend that dogs stay on broad-spectrum parasite preventives all year. Flea and tick medicines are available as oral and topical products, collars, and shampoos. Oral products are chewable tablets, while topical products are ointments that go directly on the skin.

Flea collars have fallen out of favor because they are less effective than oral and topical treatments. Shampoos are also less effective and do not provide long-lasting flea protection.

These medicines are available over the counter or by prescription and contain different active ingredients to kill and repel fleas and ticks.

Getting rid of fleas can take several days to weeks. Veterinarians recommend a multipronged approach: Kill the existing fleas, prevent new infestations, and treat the environment, both indoors and outside.

If you have multiple pets, treat them at the same time. Treating inside your home involves vacuuming where flea eggs and larvae like to hide, such as cracks and crevices, and washing bedding in hot water.

Treating outdoors involves eliminating any areas where fleas could hide, such as piles of leaves and tall grass. If this process seems daunting, you can hire a pest control service. There is no single treatment that works best for all dogs.

The best flea and tick treatments for dogs vary in many ways, including how many parasites they target, active ingredients, safety restrictions, and how long they're effective.

The most desirable treatments provide long-lasting protection, target adult fleas as well as eggs and larvae, and are effective against other parasites, such as heartworm and intestinal worms.

Your veterinarian can help you select the most appropriate product for your dog. To eliminate fleas permanently, you'll need to do more than kill adult fleas. The other developmental stages, egg and larvae, must also be eliminated. Products that kill the early stages of fleas are the most effective.

Year-round flea and tick treatment is also crucial to preventing future infestations. It may take several weeks before all the fleas are gone. Both NexGard and Frontline kill fleas at all life stages, plus ticks.

Both treatments have their advantages. There are several Frontline products: Shield, Plus, and Gold. Our top choice for an OTC flea preventive is Frontline Plus, which also protects against chewing lice and helps control sarcoptic mange infestations.

Compared to Frontline Plus, NexGard kills fleas more quickly 4 hours versus 12 hours and ticks 24 hours versus 48 hours. For this reason, NexGard is a better choice for preventing the transmission of Lyme disease from ticks. Some veterinarians also use NexGard to treat mange. Flea and tick medicines are FDA-approved to be safe and effective.

However, these medicines also have safety restrictions depending on age, weight, and whether a dog is pregnant or nursing. Some treatments also have safety warnings for dogs with a history of seizures or other neurologic disorders.

As you evaluate flea and tick medicines, check the label to ensure it's safe for your dog. Some flea control products are sold over the counter, while others require a prescription. Prescription products typically cost more than OTC treatments because they protect against more parasites, including heartworms.

However, OTC options can still provide effective, long-lasting treatment against fleas and other parasites. Yes, OTC treatments are available without a prescription. These medicines usually do not protect against as many parasites as prescription flea and tick products.

Flea collars work but are generally less effective than topical or oral treatments. Seresto Flea and Tick Collar for Dogs provides eight months of protection against adult fleas, flea larvae, ticks, and mange mites. Lay recommends flea collars for dogs that cannot tolerate topical or oral flea products.

In March , USA Today and the Midwest Center for Investigative Reporting published a report alleging that the Seresto flea collar is linked to thousands of adverse incidents in pets and humans. To date, 2, pet deaths have been allegedly linked to the collar. Elanco published a statement defending the collar's safety and efficacy.

The American Veterinary Medical Association AVMA and Pet Poison Hotline followed suit. The EPA recommends pet owners read the entire label before using any flea collar and follow all directions carefully. Your veterinarian can provide additional safety guidance. Purchase a Seresto collar only from a reputable online retailer, brick-and-mortar store with a guarantee program, or your veterinarian.

To verify product authenticity, call Elanco product support at If your pet has an adverse reaction, immediately remove the collar and call your veterinarian. Fleas are hard to see with the naked eye. Look for signs of a flea infestation on your dog, including nonstop biting, scratching, or licking and red, irritated skin.

Flea dirt, a rust-colored mixture of blood meal and dried feces, is a telltale sign of fleas and can be found in places your dog spends time, such as their bed.

Running a flea comb against the direction of your dog's fur can pick up the dirt. You can often see it on your dog in hard-to-reach places like the base of the tail, middle of the back, and groin. Other signs include pale gums, which are a sign of anemia, and patches of hair loss.

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Copy Link. This article was medically reviewed by Karie Johnson, DVM, a veterinarian in the south suburbs of Chicago whose focus is on nutrition, osteoarthritis, behavior, and end-of-life care.

Reduced pet flea and tick treatments - A few of the best-loved flea medications are Credelio, Sentinel, Advantus, Capstar, Trifexis, Comfortis, Simparica, Nexgard, and Bravecto. Tractor Supply Flea & Tick Control (40 Products Found) · Bravecto · Nexgard · Simparica Chewables · Revolution · Seresto Dog Collar · Simparica TRIO · Advantage Multi Flea and Tick Control for Dogs ; Nexgard. $ ; Bravecto. $ ; Frontline Plus. $ ; Simparica Chewables. $ ; Nexgard Spectra. $ Preventer Plus (Milbemycin oxime & Lufenuron) · Generic Advantage Multi (Imidacloprid & Moxidectin) · Revolution for Cats & Dogs · Generic Revolution for Cats

Variants: Revolution for Dogs 5. Frontline Plus is our favorite non-prescription topical treatment, and it protects against fleas and a range of tick species. For dosing that is suitable for dogs of other weights, see below. This monthly non-prescription topical treatment for cats protects against the same pests as its counterpart for dogs and requires the same monthly schedule.

Consider this treatment if you have both dogs and cats, and you want to protect them from the same set of pests, on the same schedule. What it treats: Frontline Plus is the only flea and tick treatment we recommend that treats the same pests for cats or dogs, on the same timetable, without a prescription.

Both treatments fight fleas, lice, lone star ticks, American dog ticks, deer ticks, and brown dog ticks. Comparatively, Bravecto offers four formulas that protect against different combinations of pests, with less coverage in its cat products; this can get confusing for pet owners of both cats and dogs that want to protect their pets from several parasites with a single dose.

Frontline Plus takes out the guesswork so pet owners can focus on playtime rather than on flea-bath time. So you can quickly pick up a new box while running errands without worrying if your vet filled the prescription.

Variants: Frontline Plus for Dogs 5 to 22 pounds , 23 to 44 pounds , 45 to 88 pounds , 89 to pounds ; Frontline Plus for Cats over 1. This flea collar lasts up to eight months, and it protects against the same fleas and ticks as the dog version—but not lice and mange.

The Seresto Collar for Dogs and Seresto Collar for Cats both provide protection that lasts as long as possible between reapplications eight months per collar, compared with one month for most topicals.

Half of our picks, including Frontline and Revolution, require monthly topical treatments. Also, some pets may not appreciate having the extra bulk of a collar around their neck. And pets with especially sensitive skin may experience side effects of redness or inflammation near the collar; if this sounds like your pet, try an oral or topical treatment instead.

Seresto Collar for Cats protects against fleas, American dog ticks, deer ticks, brown dog ticks, and lone star ticks. Seresto Collar for Dogs protects against fleas, American dog ticks, deer ticks, brown dog ticks, lone star ticks, lice, and sarcoptic mange.

Variants: Seresto Collar for Cats all pet weights ; Seresto Collar for Dogs up to 18 pounds , over 18 pounds. For this guide, I spoke with six professionals, from veterinarians to pesticide experts, about how to select the best flea and tick treatment for your pet.

I spoke with Jennifer Gervais, a pesticide specialist at the National Pesticide Information Center , and Ken Labbe, a spokesperson for the U. Environmental Protection Agency about pesticide regulation. I consulted Dr. Douglas Kratt, president of the American Veterinary Medical Association , about how to select the appropriate medication for your pet.

I asked Dr. Tierra Price, a spay-neuter surgeon and founder of the BlackDVM Network , and Dr. Jennifer Welser, chief medical officer at Mars Veterinary Health , about their favorite flea and tick medications.

And I discussed product safety with Dr. Tina Wismer, senior director of the ASPCA Animal Poison Control Center. To find the best flea and tick treatments, we spoke with six pet and pesticide experts about medications, side effects, active ingredients, and regulatory concerns.

Our two veterinarians shared their personal product recommendations and shopping advice, which guided us in this review.

They also shared the favorite treatments they recommend to their own clients. We cross-referenced their advice with dozens of treatments sold across retailers like PetMeds, Amazon, Chewy, Petco, and PetSmart, among others.

We dismissed sprays and shampoos because they offer protection for only days or a week at a time, and pet owners are more likely to misuse them compared with other products.

That left us with eight brands of chews, topicals, and collars for cats or dogs. We selected the four brands that were highly recommended by our experts, that kill and protect against a wide range of pests, and that are sold across retailers at a variety of budgets.

Pet owners who hike with their dogs have different needs than those who have house cats. All pesticides have risks, from skin irritation to seizures. We recommend only FDA-approved for ingested medications or EPA-registered for topicals treatments that both kill and protect against pests. All are regulated to ensure safety and efficacy, said Dr.

Jennifer Welser of Mars Veterinary Health. Still, anecdotes about potential reactions can leave some pet owners on guard—especially when those reactions make headlines.

The FDA has issued a fact sheet warning pet owners about adverse effects associated with some flea and tick products, including some we recommend. Troubling reactions include neurological symptoms, like tremors and seizures.

Similarly, in the EPA disclosed an increase in adverse-effect reports among topical flea and tick treatments.

In the investigation it identified 11 active ingredients, which half of our picks contain. Bravecto and Revolution do not use any of those actives.

Tina Wismer, a veterinarian and senior director of the ASPCA Animal Poison Control Center. To ensure the best outcome for flea and tick treatments, never buy medication without first consulting your veterinarian. Avoid counterfeits by buying products from your vet or a reputable retailer we like Chewy.

Follow the application instructions. Never split doses among pets. If you use a topical, keep pets separated until it dries, to avoid ingestion.

And never use dog products on cats because the dosage levels can be dangerous. Emergency situations include neurological signs, such as wobbling, walking in circles, and drooling, noted Price. If your pet does have a reaction, look for an FDA or EPA label on the box and report the problem to the appropriate agency.

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